NFκB p65 Polyclonal Antibody
- Catalog Number : A140114
- Number : A140114-50ug
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Introduction
RELA proto-oncogene, NF-kB subunit(RELA) Homo sapiens NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
General Information
| Reactivity | Human, Mouse, Monkey |
|---|---|
| Application | WB, IF, ELISA, ICC, IHC-p |
| Host | Rabbit |
| Clonality | Polyclonal |
| Uniprot | Human Q04206；Mouse Q04207 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NF-kappaB p65. AA range:275-324 |
| Assay principle | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300.Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinitychromatography using epitope-specific immunogen. |
| Formula | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instruction | -20°C/1 year |
| Alias | RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 |
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