General Information
Application | Inhibitor |
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Description | LEE011 succinate is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
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Cas NO. | 1374639-75-4 |
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Purity | ≥98% |
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Molecular Weight |
552.63 |
Formula | C27H36N8O5 |
Solubility |
DMSO : > 20mg/ml |
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Alias | N/A |
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Target / IC50 |
CDK4 : 10 nM CDK6 : 39 M |
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Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
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|
1 mg |
5 mg |
10 mg |
|
1 mM |
1.8095 mL | 9.0476 mL | 18.0953 mL | |
5 mM | 0.3619 mL | 1.8095 mL | 3.6191 mL | |
10 mM | 0.1810 mL | 0.9048 mL | 1.8095 mL |