General Information
| Application | Inhibitor |
|---|
| Description | LEE011 succinate is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
|---|
| Cas NO. | 1374639-75-4 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight |
552.63 |
| Formula | C27H36N8O5 |
| Solubility |
DMSO : > 20mg/ml |
|---|
| Alias | N/A |
|---|
| Target / IC50 |
CDK4 : 10 nM CDK6 : 39 M |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.8095 mL | 9.0476 mL | 18.0953 mL | |
| 5 mM | 0.3619 mL | 1.8095 mL | 3.6191 mL | |
| 10 mM | 0.1810 mL | 0.9048 mL | 1.8095 mL | |
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