Introduction
Biochemical research.
Tretinoin (ATRA) is a ligand for the Retinoid X receptor (RAR) and Retinoid X receptor (RXR), combining RAR and RXR as transduction factors to regulate the growth and differentiation of normal cells and tumor cells. Cytochrome P450s (CYPs) catalyze the hydroxylation of ATRA; retinoic acid guides embryonic stem cells to evolve into neurons
Tretinoin (ATRA) is a ligand for the Retinoid X receptor (RAR) and Retinoid X receptor (RXR), combining RAR and RXR as transduction factors to regulate the growth and differentiation of normal cells and tumor cells. Cytochrome P450s (CYPs) catalyze the hydroxylation of ATRA; retinoic acid guides embryonic stem cells to evolve into neurons
General Information
| Application | Cell, Chemical |
|---|---|
| Cas No. | 302-79-4 |
| Purity | ≥98% (HPLC) |
| Molecular Weight | 300.44 |
| Formula | C20H28O2 |
| Solubility | Insoluble in water, soluble in DMSO |
| Storage instruction | Store at -20°C |
| Alias | ATRA；Tretinoin；Vitamin A acid；all-trans-Retinoic acid |
| Grade |
BR |
|---|
| Melting Point |
180～181℃ |
|---|
| Appearance |
Yellow powder |
|---|
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