COVID-19 
, COVID-19 Related Compounds
Telaprevir (VX-950)
- Catalog Number : C5139
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Introduction
VX-950 is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it demonstrated excellent antiviral activity both in genotype 1b HCV replicon cells (50% inhibitory concentration [IC50] = 354 nM) and in human fetal hepatocytes infected with genotype 1a HCV-positive patient sera (IC50 = 280 nM). VX-950 Forms a covalent but reversible complex with the genotype 1a HCV NS3-4A protease in a slow-on, slow-off process with a steady-state inhibition constant (Ki*) of 7 nM. For the detailed information about the solubility of Telaprevir (VX-950) in water, the solubility of Telaprevir (VX-950) in DMSO, the solubility of Telaprevir (VX-950) in PBS buffer, the animal experiment（test） of Telaprevir (VX-950),the in vivo,in vitro and clinical trial test of Telaprevir (VX-950),the cell experiment（test） of Telaprevir (VX-950),the IC50, EC50 and Affinity of Telaprevir (VX-950), please contact DC Chemicals.
General Information
| Cas No. | 402957-28-2 |
|---|---|
| Purity | 0.99 |
| Molecular Weight | 679.85 |
| Formula | C36H53N7O6 |
| Solubility | DMSO : ≧ 50 mg/mL/ H2O：< 0.1 mg/mL |
| Storage instruction | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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