COVID-19 , COVID-19 Related Compounds
Furin Inhibitor
- Catalog Number : C5117
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Introduction
Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki = 0.12 nM). Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent.In addition, it inhibits furin-dependent pro-MMP-2 activation in mononuclear inflammatory cells.
General Information
Cas No. | 150113-99-8 |
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Purity | >98% |
Molecular Weight | 744.4 |
Formula | C34H66ClN11O5 |
Storage instruction | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |