ITGA4 Polyclonal Antibody
- Catalog Number : A340716
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Introduction
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P13612 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the Internal region of human Integrin α4. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | 269C wild type,Antigen CD49D,alpha 4 subunit of VLA 4 receptor,CD49 antigen like family member D,CD49 antigen-like family member D,CD49d,IA4,Integrin alpha 4,Integrin alpha 4 subunit,Integrin alpha IV,Integrin alpha-4,Integrin alpha-IV,Integrin,alpha 4 (antigen CD49D,alpha 4 subunit of VLA 4 receptor),ITA4,ITGA4,MGC90518,OTTHUMP00000205320,Very late activation protein 4 receptor,alpha 4 subunit,VLA 4 subunit alpha,VLA-4 subunit alpha,VLA4 |
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