EEA1 Polyclonal Antibody
- Catalog Number : A340705
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Introduction
EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking. The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes. The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin. Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion.
General Information
| Reactivity | Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q15075 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the N-terminal region of human EEA1. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | Early endosome antigen 1,Early endosome antigen 1,162kD,Early endosome associated protein,EEA 1,EEA1,EEA1,Endosome associated protein p162,Endosome-associated protein p162,MST105,MSTP105,ZFYVE2,Zinc finger FYVE domain containing protein 2,Zinc finger FYVE domain-containing protein 2 |
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