SIRT1 Polyclonal Antibody
- Catalog Number : A340669
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Introduction
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
General Information
| Reactivity | Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q96EB6 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human SIRT1 around the non-phosphorylation site of Ser47. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | 75SirT1,hSIR2,hSIRT1,HST2,S. cerevisiae,homolog of,NAD dependent deacetylase sirtuin 1,NAD dependent protein deacetylase sirtuin 1,OTTHUMP00000198111,OTTHUMP00000198112,Regulatory protein SIR2 homolog 1,SIR1,SIR2,SIR2 like 1,SIR2 like protein 1,SIR2,S.cerevisiae,homolog-like 1,SIR2-like protein 1,SIR2ALPHA,SIR2L1,Sirt1,SirtT1 75 kDa fragment,Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae),Sirtuin 1,Sirtuin type 1 |
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