PIAS3 Polyclonal Antibody
- Catalog Number : A340639
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Introduction
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q9Y6X2 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the N-terminal region of human PIAS 3 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | E3 SUMO protein ligase PIAS 3,E3 SUMO protein ligase PIAS3,E3 SUMO-protein ligase PIAS3,FLJ14651,OTTHUMP00000015586,OTTHUMP00000015587,PIAS 3,Pias3,PIAS3 protein,PIAS3,Protein inhibitor of activated STAT 3,Protein inhibitor of activated STAT protein 3,Protein inhibitor of activated STAT3,Zinc finger MIZ type containing 5,ZMIZ 5,ZMIZ5 |
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