PFKFB2 Polyclonal Antibody
- Catalog Number : A340632
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Introduction
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | O60825 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human PFK-2 car around the non-phosphorylation site of S483. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | PFKFB2,6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2,6PF-2-K/Fru-2,6-P2ase 2,PFK/FBPase 2,6PF-2-K/Fru-2,6-P2ase heart-type isozyme |
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