P38 Polyclonal Antibody
- Catalog Number : A340613
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Introduction
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q16539 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human p38 around the non-phosphorylation site of Thr180/Tyr182. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | CSAID Binding Protein 1,CSAID binding protein,CSAID-binding protein,Csaids binding protein,CSBP 1,CSBP 2,CSBP,CSBP1,CSBP2,CSPB1,Cytokine suppressive anti-inflammatory drug-binding protein,EXIP,MAP kinase 14,MAP kinase MXI2,MAP kinase p38 alpha,MAPK 14,MAPK14,MAX interacting protein 2,MAX-interacting protein 2,Mitogen Activated Protein Kinase 14,Mitogen activated protein kinase p38 alpha,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase p38 alpha,MK14,Mxi 2,MXI2,p38 ALPHA,p38,p38 MAP kinase,p38 MAPK,p38 mitogen activated protein kinase,p38ALPHA,p38alpha Exip,PRKM14,PRKM15,RK,SAPK2A |
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