IRAK1 Polyclonal Antibody
- Catalog Number : A340567
- Number :
-
Size:
Qty : - Price : Request 詢價
- Stock : Request
-
Introduction
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IF, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P51617 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human IRAK-1 around the non-phosphorylation site of Thr387. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | AA48924,Il1rak,Interleukin 1 receptor associated kinase 1,Interleukin-1 receptor-associated kinase 1,IRAK,IRAK-1,Irak1,IRAK1-S,IRAK1,mPLK,OTTHUMP00000026014,OTTHUMP00000026015,OTTHUMP00000026020,OTTHUMP00000180621,Pelle,Pelle homolog,Pelle-like protein kinase,Plpk |
.png)