GTBP Polyclonal Antibody
- Catalog Number : A340537
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Introduction
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines witHuman, MouseSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
General Information
| Reactivity | Mouse, Monkey |
|---|---|
| Application | WB, IF, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P52701 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the Internal region of human GTBP |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | DNA mismatch repair protein Msh6,G/T mismatch binding protein,G/T mismatch-binding protein,GTBP,GTMBP,hMSH6,HNPCC 5,HNPCC5,HSAP,MSH 6,MSH6,MSH6,mutS (E. coli) homolog 6,MutS alpha 160 kDa subunit,MutS homolog 6 (E. coli),mutS homolog 6,MutS-alpha 160 kDa subunit,p160,Sperm associated protein |
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