EOMES Polyclonal Antibody
- Catalog Number : A340508
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Introduction
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.EOMES (Eomesodermin) is a Protein Coding gene. Diseases associated with EOMES include Microcephaly-Polymicrogyria-Corpus Callosum Agenesis Syndrome and Microcephaly With Polymicrogyria. Among its related pathways are Mesodermal Commitment Pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is TBR1.
General Information
| Reactivity | Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | O95936 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the N-terminal region of human EOMES. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | eomes,EOMES,Eomesodermin,Eomesodermin homolog,t box brain 2,T-box brain protein 2,T-brain-2,Tbr 2,TBR-2 |
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