Phospho-PAK2 (Ser20) Polyclonal Antibody
- Catalog Number : A340351
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Introduction
The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway. Cleaved PAK-2p34 seems to have a higher activity than the CDC42-activated form.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q13177 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human PAKγ around the phosphorylation site of S20. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | -t-PAK2,CB422,EC 2.7.11.1,Gamma PAK,Gamma-PAK,hPAK65,Kinase,p21 (CDKN1A) activated kinase 2,p21 (CDKN1A)-activated kinase 2a,p21 activated kinase 2,p21 protein (Cdc42/Rac)-activated kinase 2,p21 protein Cdc42 Rac activated kinase 2,p21-activated kinase 2,p21-activated kinase,65-KD,p21-activated protein kinase I,p21CDKN1A activated kinase 2,p27,p34,p58,p65PAK,PAK 2,PAK-2,PAK-2p34,Pak2,PAK2,PAK65,PAKgamma,S6 H4 kinase,S6/H4 kinase,Serine threonine protein kinase PAK 2,Serine/threonine protein kinase PAK 2 |
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