BMI1 Polyclonal Antibody
- Catalog Number : A340142
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Introduction
BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
General Information
| Reactivity | Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P35226 |
| Immunogen | Recombinant protein of human BMI1 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | B lymphoma Mo MLV insertion region (mouse),B lymphoma Mo MLV insertion region 1 homolog,Bmi 1,BMI1,BMI1 polycomb ring finger oncogene,BMI1,Flvi 2/bmi 1,FLVI2/BMI1,MGC12685,Murine leukemia viral (bmi 1) oncogene homolog,Oncogene BMI 1,PCGF 4,PCGF4,Polycomb complex protein BMI 1,Polycomb complex protein BMI-1,Polycomb group protein Bmi1,Polycomb group ring finger 4,Polycomb group RING finger protein 4,RING finger protein 51,RNF 51,RNF51 |
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