General Information
| Application | Inhibitor |
|---|
| Description | Ko 143 is a potent and selective ABCG2 (breast cancer resistance protein multidrug transporter, BCRP) inhibitor (EC90 = 26 nM). It displays > 200-fold selectivity over P-gp and MRP-1 transporters. Ko 143 also increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. |
|---|
| Target |
Autophage |
|---|
| Cas NO. | 461054-93-3 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight |
469.57 |
| Formula | C26H35N3O5 |
| Solubility |
DMSO : 10 mM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
|---|
| Alias | N/A |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.1296 mL | 10.6480 mL | 21.2961 mL | |
| 5 mM | 0.4259 mL | 2.1296 mL | 4.2592 mL | |
| 10 mM | 0.2130 mL | 1.0648 mL | 2.1296 mL | |
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