General Information
| Application | Inhibitor |
|---|
| Description | Naftopidil is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia. |
|---|
| Cas NO. | 571419-07-2 |
|---|
| Purity | ≥99% |
|---|---|
| Molecular Weight | 392.49 |
| Formula | C24H28N2O3 |
| Solubility |
DMSO : 79 mg/mL Ethanol : Insoluble Water : Insoluble |
|---|
| Target / IC50 |
α1A-adrenergic receptor : 3.7 nM α1B-adrenergic receptor : 20 nM α1D-adrenergic receptor : 1.2 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
| Alias |
KT-611 |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.5478 mL | 12.7392 mL | 25.4784 mL | |
| 5 mM | 0.5096 mL | 2.5478 mL | 5.0957 mL | |
| 10 mM | 0.2548 mL | 1.2739 mL | 2.5478 mL | |
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