General Information
| Application | Inhibitor |
|---|
| Description | Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. |
|---|
| Cas NO. | 119413-54-6 |
|---|
| Purity | ≥99% (HPLC) |
|---|---|
| Molecular Weight | 457.91 |
| Formula | C23H23N3O5.HCl |
| Solubility |
DMSO : 91 mg/mL Ethanol : Insoluble Water : 91 mg/mL |
|---|
| Target / IC50 |
Topo I (DU-145 Luc cell) : 2 nM Topo I (MCF-7 Luc cell) : 13 nM |
|---|
| Alias | NSC609699, Nogitecan HCl, SKFS 104864A |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.1838 mL | 10.9192 mL | 21.8384 mL | |
| 5 mM | 0.4368 mL | 2.1838 mL | 4.3677 mL | |
| 10 mM | 0.2184 mL | 1.0919 mL | 2.1838 mL | |
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