General Information
| Application | Inhibitor |
|---|
| Description | MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively; no inhibitory activities against 250 other protein kinases observed. Phase 2. |
|---|
| Cas NO. | 1032350-13-2 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 480.39 |
| Formula | C25H21N5O.HCl |
| Solubility |
DMSO : 92 mg/mL Ethanol : 1.8 mg/mL Water : 92 mg/mL |
|---|
| Alias | N/A |
|---|
| Target / IC50 |
Akt1 : 8 nM Akt2 : 12 nM Akt3 : 65 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.0816 mL | 10.4082 mL | 20.8164 mL | |
| 5 mM | 0.4163 mL | 2.0816 mL | 4.1633 mL | |
| 10 mM | 0.2082 mL | 1.0408 mL | 2.0816 mL | |
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