General Information
Application | Inhibitor |
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Description | LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50=0.011 μM) and also inhibits other transcription kinases CDK8 (IC50=0.016 μM) and CDK7 (IC50=0.246 μM). |
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Cas NO. | 1619903-54-6 |
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Purity | ≥98% |
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Molecular Weight | 448.60 |
Formula | C26H36N6O |
Solubility |
DMSO : 23 mg/mL Ethanol : 42 mg/mL Water : Insoluble |
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Alias | N/A |
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Target / IC50 |
CDK7 : 0.246 μM CDK8 : 0.016 μM CDK9 : 0.011 μM |
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Storage |
Powder : -20°C for 3 years |
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|
1 mg |
5 mg |
10 mg |
|
1 mM |
2.2292 mL | 11.1458 mL | 22.2916 mL | |
5 mM | 0.44589 mL | 2.2292 mL | 4.4583 mL | |
10 mM | 0.2229 mL | 1.1146 mL | 2.2292 mL |