General Information
| Application | Inhibitor |
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| Description | Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively. It also blocks thymidine (dThd) DNA incorporation. Phase 3. |
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| Cas NO. | 779353-01-4 |
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| Purity | ≥98% |
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| Molecular Weight | 561.71 |
| Formula | C21H28N6O2 |
| Solubility |
DMSO : ≥56 mg/mL Ethanol : 8 mg/mL Water : Insoluble |
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| Alias | SCH727965 |
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| Target / IC50 |
CDK1 : 3 nM CDK2 : 1nM CDK5 : 1 nM CDK9 : 4 nM |
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| Storage |
Powder : -20°C for 3 years |
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|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.7803 mL | 8.9014 mL | 17.8028 mL | |
| 5 mM | 0.3561 mL | 1.7803 mL | 3.5606 mL | |
| 10 mM | 0.1780 mL | 0.8901 mL | 1.7803 mL | |
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