General Information
| Application | Inhibitor |
|---|
| Description | Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. Phase 1/2. |
|---|
| Cas NO. |
1260251-31-7 |
|---|
| Purity | ≥99% |
|---|---|
| Molecular Weight | 806.94 |
| Formula | C42H56F2N8O6 |
| Solubility |
DMSO : 100 mg/mL Ethanol : 55 mg/mL Water : Insoluble |
|---|
| Alias |
TL32711 |
|---|
| Target / IC50 |
cIAP1 : <1 nM XIAP : 45 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.2392 mL | 6.1962 mL | 12.3925 mL | |
| 5 mM | 0.2478 mL | 1.2392 mL | 2.4785 mL | |
| 10 mM | 0.1239 mL | 0.6196 mL | 1.2392 mL | |
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