General Information
| Application | Inhibitor |
|---|
| Description | Citarinostat (ACY-241) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3. |
|---|
| Cas NO. |
1316215-12-9 |
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| Purity | 98% |
|---|---|
| Molecular Weight | 467.95 |
| Formula | C24H26ClN5O3 |
| Solubility |
DMSO : 93 mg/mL Ethanol : 41 mg/mL Water : Insoluble |
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| Storage |
Powder : -20°C for 3 years |
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| Target / IC50 |
HDAC1 : 35 nM HDAC2 : 45 nM HDAC3 : 46 nM HDAC6 : 2.6 nM HDAC8 : 137 nM |
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|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.1370 mL | 10.6849 mL | 21.3698 mL | |
| 5 mM | 0.4274 mL | 2.1370 mL | 4.2740 mL | |
| 10 mM | 0.2137 mL | 1.0685 mL | 2.1370 mL | |
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