General Information
| Application | Inhibitor |
|---|
| Description | PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. |
|---|
| Cas NO. |
167869-21-8 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 958.22 |
| Formula | C16H13NO3 |
| Solubility |
DMSO: 16 mg/mL H2O: < 0.01 mg/mL |
|---|
| Target / IC50 | MEK : 5 μM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
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|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
3.7414 mL | 18.7070 mL | 37.4139 mL | |
| 5 mM | 0.7483 mL | 3.7414 mL | 7.4828 mL | |
| 10 mM | 0.3741 mL | 1.8707 mL | 3.7414 mL | |
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