General Information
| Application | Inhibitor |
|---|
| Description | Everolimus is a targeted, highly specific agent with an IC50 for binding to isolated FKBP-12, or FKBP-12 complexed to mTOR of 5 to 6 nM, and no significant activity against other protein kinases. |
|---|
| Cas NO. |
159351-69-6 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 958.22 |
| Formula | C53H83NO14 |
| Solubility |
DMSO: ≥ 54 mg/mL Everolimus is dissolved in 30% (w/v) Captisol |
|---|
| Target / IC50 | mTOR : 5-6 nM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : The compound is unstable in solutions, freshly prepared is recommended. |
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|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.0436 mL | 5.2180 mL | 10.4360 mL | |
| 5 mM | 0.2087 mL | 1.0436 mL | 2.0872 mL | |
| 10 mM | 0.1044 mL | 0.5218 mL | 1.0436 mL | |
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