General Information
| Application | Inhibitor |
|---|
| Cas NO. |
915087-33-1 |
|---|
| Purity | ≥99% |
|---|---|
| Molecular Weight | 489.99 |
| Formula | C21H16F4N4O2S |
| Solubility | DMSO: 10 mM |
|---|
| Description | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. |
|---|
| Target / IC50 | AR : 36 nM |
|---|
| Alias | MDV3100 |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
|---|
| In vivo |
Enzalutamide induces great tumor regression in castrate male mice bearing LNCaP/AR xenografts at a dose of 10 mg/kg. |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.1531 mL | 10.7657 mL | 21.5313 mL | |
| 5 mM | 0.4306 mL | 2.1531 mL | 4.3063 mL | |
| 10 mM | 0.2153 mL | 1.0766 mL | 2.1531 mL | |
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