General Information
| Application | Inhibitor |
|---|
| Cas NO. |
1062368-24-4 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 406.48 |
| Formula | C25H22N6 |
| Solubility |
DMSO : Insoluble Ethanol : 1 mg/ml H2O : Insoluble |
|---|
| Description | LDN193189 is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. |
|---|
| Target / IC50 |
ALK2 : 5 nM ALK3 : 30 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.4601 mL |
12.3007 mL |
24.6015 mL |
|
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