General Information
| Application | Inhibitor |
|---|
| Cas NO. |
391210-10-9 |
|---|
| Purity | ≥99% |
|---|---|
| Molecular Weight | 482.19 |
| Formula | C16H14F3IN2O4 |
| Solubility |
DMF : 25 mg/ml DMSO : 96 mg/ml Ethanol : 40 mg/ml Methanol : 40 mg/ml H2O : Insoluble |
|---|
| Description | PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 1/2. |
|---|
| Target / IC50 | mTOR : ~0.1 nM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.0739 mL |
10.3694 mL |
20.7387 mL |
|
|
5 mM |
0.4148 mL |
2.0739 mL |
4.1477 mL |
|
|
10 mM |
0.0415 mL |
0.2074mL |
0.4148 mL |
|
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