General Information
Application | Inhibitor |
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Cas NO. |
915087-33-1 |
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Purity | ≥99% |
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Molecular Weight | 489.99 |
Formula | C21H16F4N4O2S |
Solubility | DMSO: 10 mM |
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Description | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. |
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Target / IC50 | AR : 36 nM |
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Alias | MDV3100 |
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Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
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In vivo |
Enzalutamide induces great tumor regression in castrate male mice bearing LNCaP/AR xenografts at a dose of 10 mg/kg. |
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|
1 mg |
5 mg |
10 mg |
|
1 mM |
2.1531 mL | 10.7657 mL | 21.5313 mL | |
5 mM | 0.4306 mL | 2.1531 mL | 4.3063 mL | |
10 mM | 0.2153 mL | 1.0766 mL | 2.1531 mL |