Recombinant Human Transforming Growth Factor Beta 1(TGFβ1) Protein
- Catalog Number : P0073
- Number : P0073
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Introduction
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
General Information
| Reactivity | Human |
|---|---|
| Host | Human |
| Uniprot | P01137 |
| Purity | >95% (SDS-PAGE) |
| Molecular Weight | 12.8 kDa |
| Formula | Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH2.5. |
| Storage instruction | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
| Alias | Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide;LAP; TGFB1; TGFB;CED;DPD1;TGF-beta 1 |
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