COVID-19 
, COVID-19 Related Compounds
Remdesivir metabolite(GS-441524)
- Catalog Number : C5131
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Introduction
Remdesivir metabolite.Remdesivir blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 Nm,and also showed potent activity blocking 2019-nCov(Coronavirus). Remdesivir, also known as GS-5734, is an antiviral drug, and a novel nucleotide analog prodrug. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h. GS-5734 inhibits both epidemic and zoonotic coronaviruses. It was developed by Gilead Sciences as a treatment for filovirus infections such as Ebola virus disease and Marburg virus.
General Information
| Cas No. | 1191237-69-0 |
|---|---|
| Purity | >99% |
| Molecular Weight | 291.09 |
| Formula | C12H13N5O4 |
| Solubility | DMSO : 125 mg/mL |
| Storage instruction | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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