PIAS1 Polyclonal Antibody

Catalog Number : A340638
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Introduction

This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.

General Information

Reactivity	Mouse
Application	WB, IHC, ELISA
Clonality	Polyclonal
Conjugate	Non-conjugated
Uniprot	O75925
Isotype	IgG
Immunogen	Synthetic peptide of human PIAS1
Storage buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction	Store at -20℃. Avoid freeze / thaw cycles.
Alias	AR interacting protein,DDXBP1,DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1,DEAD/H box binding protein 1,DEAD/H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu binding protein,Gu-binding protein,GU/RH-II,Pias1,PIAS1,Protein inhibitor of activated STAT protein 1,Protein inhibitor of activated STAT,1,RNA helicase II binding protein,RNA helicase II-binding protein,Zinc finger,MIZ-type containing 3,ZMIZ3