PRKN Polyclonal Antibody
- Catalog Number : A340621
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Introduction
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
General Information
| Application | WB, IHC, ELISA |
|---|---|
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | O60260 |
| Isotype | IgG |
| Immunogen | Recombinant protein of human PARK2 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | AR JP,E3 ubiquitin ligase,E3 ubiquitin protein ligase parkin,E3 ubiquitin-protein ligase parkin,FRA6E,LPRS 2,LPRS2,PARK 2,Park2,Parkin 2,Parkinson disease (autosomal recessive juvenile) 2,Parkinson disease (autosomal recessive,juvenile) 2,parkin,Parkinson disease protein 2,Parkinson juvenile disease protein 2,Parkinson protein 2 E3 ubiquitin protein ligase,Parkinson protein 2,E3 ubiquitin protein ligase (parkin),PDJ,PRKN 2,PRKN,PRKN2,PRKN2,Ubiquitin E3 ligase PRKN |
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