General Information
Application | Inhibitor |
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Description | MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively; no inhibitory activities against 250 other protein kinases observed. Phase 2. |
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Cas NO. | 1032350-13-2 |
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Purity | ≥99% |
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Molecular Weight | 480.39 |
Formula | C25H23Cl2N5O |
Solubility |
DMSO : 4.8 mg/mL |
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Alias | N/A |
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Target / IC50 |
Akt1 : 5 nM Akt2 : 12 nM Akt3 : 65 nM |
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Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
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|
1 mg |
5 mg |
10 mg |
|
1 mM |
2.0816 mL | 10.4082 mL | 20.8164 mL | |
5 mM | 0.4163 mL | 2.0816 mL | 4.1633 mL | |
10 mM | 0.2082 mL | 1.0408 mL | 2.0816 mL |