General Information
| Application | Inhibitor |
|---|
| Description | GDC-0941 is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).Phase 2 |
|---|
| Cas NO. | 957054-30-7 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 513.64 |
| Formula | C23H27N7O3S2 |
| Solubility |
DMSO : ≥100 mg/mL Ethanol : <1.2 mg/mL Water : ≥1.2 mg/mL |
|---|
| Target / IC50 |
p110α : 3 nM p110β : 33 nM p110γ : 75 nM p110δ : 3 nM mTOR : 0.58 μM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
|---|
| Alias | RG7321, GDC-0941 |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.9469 mL | 9.7344 mL | 19.4689 mL | |
| 5 mM | 0.3894 mL | 1.9469 mL | 3.8938 mL | |
| 10 mM | 0.1947 mL | 0.9734 mL | 1.9469 mL | |
.png)