General Information
| Application | Inhibitor |
|---|
| Description |
SN-38 is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. |
|---|
| Cas NO. |
86639-52-3 |
|---|
| Purity | 98% |
|---|---|
| Molecular Weight | 392.4 |
| Formula | C22H20N2O5 |
| Solubility |
DMSO : 21 mg/mL Ethanol : Insoluble Water : Insoluble |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
| Target / IC50 |
Topo I |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.5484 mL | 12.7421 mL | 25.4842 mL | |
| 5 mM | 0.5097 mL | 2.5484 mL | 5.0968 mL | |
| 10 mM | 0.2548 mL | 1.2742 mL | 2.5484 mL | |
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