Phospho NFκB/p-NFκB p65 (Ser536) Polyclonal Antibody
- Catalog Number : A340004
- Number : A340004-20ug
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Introduction
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by
specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is
composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the
product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is
composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the
product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
General Information
| Reactivity | Human, Mouse, Rabbit |
|---|---|
| Application | WB, IHC |
| Host | Rabbit |
| Conjugate | Non-conjugated |
| Uniprot | Q04206 |
| Isotype | IgG |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S536 of human NF-kB p65 |
| Assay principle | WB 1:500-1:1000 IHC 1:50-1:100 |
| Purity | Affinity purification |
| Molecular Weight | 71kDa |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage instruction | Store at -20°C. Avoid freeze / thaw cycles. |
| Alias | NFKB3,p65,NF-kB p65,RELA,CMCU |
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