MAGE-C1(ABT-MAGEC1) mouse mAb
- Catalog Number : A130232
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Introduction
Specificity：
This antibody detects endogenous levels of human Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended.
Background：
MAGE family member C1(MAGEC1) Homo sapiens This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.
Function：
Similarity: Contains 1 MAGE domain.,
Tissue specificity: Expressed in testis and in tumors of a wide variety of histologic types.
Subcellular Location：Cytoplasmic
This antibody detects endogenous levels of human Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended.
Background：
MAGE family member C1(MAGEC1) Homo sapiens This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.
Function：
Similarity: Contains 1 MAGE domain.,
Tissue specificity: Expressed in testis and in tumors of a wide variety of histologic types.
Subcellular Location：Cytoplasmic
General Information
| Reactivity | Human |
|---|---|
| Application | WB, IHC |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Non-conjugated |
| Uniprot | O60732 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human MAGE-C1 |
| Assay principle | IHC-p 1:100-500，WB 1:500-2000 |
| Sample type | paraffin section |
| Purity | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Expression region | Melanoma, testis |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instruction | -20°C/1 year |
| Alias | MAGEC1 |
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