Recombinant Human Gamma-glutamyl hydrolase (GGH)
- Catalog Number : P0054
- Number : P0054-20ug
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Size:
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Introduction
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
General Information
| Reactivity | Human |
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| Host | E.coli |
| Uniprot | Q92820 |
| Purity | >85% (SDS-PAGE) |
| Storage buffer | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Storage instruction | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Alias | Conjugase; folylpolygammaglutamyl hydrolase; gamma glutamyl hydrolase; Gamma-Glu-X carboxypeptidase; Gamma-glutamyl hydrolase (conjugase; folylpolygammaglutamyl hydrolase); Gamma-glutamyl hydrolase; GGH; GGH_HUMAN; gH |
| Physical Appearance |
Lyophilized powder |
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| Target Protein Sequence |
RPHGDT AKKPIIGILM QKCRNKVMKN YGRYYIAASY VKYLESAGAR VVPVRLDLTE KDYEILFKSI NGILFPGGSV DLRRSDYAKV AKIFYNLSIQ SFDDGDYFPV WGTCLGFEEL SLLISGECLL TATDTVDVAM PLNFTGGQLH SRMFQNFPTE LLLSLAVEPL TANFHKWSLS VKNFTMNEKL KKFFNVLTTN TDGKIEFIST MEGYKYPVYG VQWHPEKAPY EWKNLDGISH APNAVKTAFY LAEFFVNEAR KNNHHFKSES EEEKALIYQF SPIYTGNISS FQQCYIFD |
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| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
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