COVID-19 
, COVID-19 Related Compounds
GRL-0617
- Catalog Number : C5120
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Introduction
GRL-0617 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 0.6 uM, Ki of 0.49 uM; inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 14.5 uM, has no associated cytotoxicity and no inhibition for host DUBs (human deubiquitinating enzymes HAUSP, USP18, UCH-L1, UCH-L3). SARS-CoV Infection Preclinical
General Information
| Cas No. | 1093070-16-6 |
|---|---|
| Purity | >98% |
| Molecular Weight | 304.393 |
| Formula | C20H20N2O |
| Solubility | DMSO : 125 mg/mL |
| Storage instruction | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Alias | GRL0617;GRL 0617 |
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