Recombinant Human ACE2 protein, His Tag
- Catalog Number : P0051
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Introduction
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin, and angiotensin II to angiotensin. ACE-2 is also able to hydrolyze apelin and dynorphin with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. The recombinant Human ACE2 protein, His Tag consists of 734 amino acids and predicts a molecular mass of 85.1 kDa.
General Information
| Tested Cell | HEK293 Cells |
|---|---|
| Purity | >95% as determined by SDS-PAGE |
| Molecular Weight | 85.1 kDa |
| Formula | Lyophilized from sterile PBS, pH 7.4. |
| Solubility | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ |
| Expression region | Sequence Met1-Ser740 |
| Protein Info | Human ACE2 |
| Tag Info | 6XHis-Tag |
| Storage instruction | Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid re |
| Alias | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2 |
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