Neurofilament Polyclonal Antibody
- Catalog Number : A340709
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Introduction
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P07196 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the C-terminal region of human NF-L. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | 68 kDa neurofilament protein,68kDa neurofilament protein,CMT1F,CMT2E,FLJ53642,Light molecular weight neurofilament protein,NEFL,Neurofilament light,Neurofilament light polypeptide 68kDa,Neurofilament light polypeptide,Neurofilament protein,light chain,Neurofilament subunit NF L,Neurofilament triplet L protein,NF-L,NF68,NFL,NFL |
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