KAT2B Polyclonal Antibody
- Catalog Number : A340624
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Introduction
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
General Information
Reactivity | Rat, Mouse |
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Application | WB, IHC, ELISA |
Clonality | Polyclonal |
Conjugate | Non-conjugated |
Uniprot | Q92831 |
Isotype | IgG |
Immunogen | Synthesized peptide derived from the C-terminal region of human PCAF |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
Alias | CAF,CREBBP associated factor,GCN5,GCN5L,GCN5L1,Histone acetylase PCAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF,K(lysine) acetyltransferase 2B,KAT2B,KAT2B,Lysine acetyltransferase 2B,P,P/CAF,p300/CBP associated factor,P300/CBP-associated factor,Pcaf |