Antibody, Primary Antibody

c-Fos Polyclonal Antibody

  • Catalog Number : A340479
  • Number : A340479-20ug
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Introduction

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

General Information

Reactivity Human, Mouse, Rabbit
Application WB, IF, ELISA, IHC-p
Host Rabbit
Clonality Polyclonal
Conjugate Non-conjugated
Uniprot Human P01100;Mouse P01101;Rat P12841
Isotype IgG
Immunogen The antiserum was produced against synthesized peptide derived from human Fos. AA range:331-380
Assay principle IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Molecular Weight 58 KD
Formula Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7

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