Primary Antibody

Glucocorticoid Receptor Polyclonal Antibody

  • Catalog Number : A340407
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Introduction

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.

General Information

Reactivity Rat, Mouse
Application WB
Clonality Polyclonal
Conjugate Non-conjugated
Uniprot P04150
Isotype IgG
Immunogen Recombinant Protein
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias GCCR,GCR,GCR,GCRST,glucocorticoid nuclear receptor variant 1,Glucocorticoid receptor,GR,GRL,Grl1,nr3c1,Nuclear receptor subfamily 3 group C member 1,nuclear receptor subfamily 3,group C,member 1 (glucocorticoid receptor)

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