Phospho-CDK1 (Tyr15) Polyclonal Antibody
- Catalog Number : A340205
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Introduction
CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2.
General Information
| Reactivity | Rat, Mouse, Monkey |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P06493 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human Cdc2 around the phosphorylation site of Tyr15 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | Cdc 2,Cdc2,CDC28A,CDK 1,CDK1,CDK1,CDKN1,CELL CYCLE CONTROLLER CDC2,Cell division control protein 2,Cell division control protein 2 homolog,Cell division cycle 2 G1 to S and G2 to M,Cell division protein kinase 1,Cell Divsion Cycle 2 Protein,Cyclin Dependent Kinase 1,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,p34 Cdk1,p34 protein kinase,P34CDC2 |
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