General Information
Application | Inhibitor |
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Description | SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. |
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Cas NO. | 152121-47-6 |
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Purity | ≥98% |
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Molecular Weight | 377.43 |
Formula | C21H16FN3OS |
Solubility |
DMSO : 50 mg/mL Ethanol : Insoluble Water : Insoluble |
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Alias | PB 203580 ; RWJ 64809 |
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Target / IC50 |
p38 MAPK : 0.3-0.5 μM PKB : 3-5 μM |
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Storage |
Powder : -20°C for 3 years |
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|
1 mg |
5 mg |
10 mg |
|
1 mM |
2.6495 mL | 13.2475 mL | 26.4950 mL | |
5 mM | 0.5299 mL | 2.6495 mL | 5.2990 mL | |
10 mM | 0.2649 mL | 1.3247 mL | 2.6495 mL |