General Information
| Application | Inhibitor |
|---|
| Cas NO. |
154447-36-6 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 307.34 |
| Formula | C19H17NO3 |
| Solubility |
DMSO : 36 mg/mL Ethanol : 21 mg/mL Water : Insoluble |
|---|
| Description | LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. |
|---|
| Target / IC50 |
p110α : 0.5 μM p110β : 0.97 μM p110δ : 0.57 μM |
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|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
3.2537 mL | 16.2686 mL | 32.5373 mL | |
| 5 mM | 0.6507 mL | 3.2537 mL | 6.5075 mL | |
| 10 mM | 0.3254 mL | 1.6269 mL | 3.2537 mL | |
| Storage |
Powder : -20°C for 3 years |
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